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[30] Hoehn MM, Yahr MD. Parkinsonism: onset, progression and mortality. Neurology 1967; 17: 749 [31] Kirsh D, Maglio P. On distinguishing between epistemic and pragmatic action. Cognitive Science 1994; 18: 513 [32] Kish SJ, Shannak K, Hornykiewicz O. Uneven patterns of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. New England Journal of Medicine 1988; 318: 876 [33] Land MF, Furneax S. The knowledge base of the oculomotor system. Philosophical Transactions of the Royal Society of London B 1997; 352: 1231 [34] Land MF, Mennie N, Rusted J. The roles of vision and eye movements in the control of activities of daily living. Perception 1999; 28: 1311 [35] Lange KW, Robbins TW, Marsden CD, James M, Owen AM, Paul GM. L-dopa withdrawal in Parkinson's disease selectively impairs cognitive performance in tests sensitive to frontal-lobe dysfunction. Psychopharmacology 1992; 107 2-3 ; : 394 404. [36] Miller EK. The prefrontal cortex: complex neural properties for complex behavior. Neuron 1999; 22: 15 [37] Morris RG, Ahmed S, Syed GM, Toone BK. Neural correlates of planning ability: frontal lobe activation in the Tower of London test. Neuropsychologia 1993; 31: 1367 [38] Morris RG, Downes JJ, Sahakian BJ, Polkey CE, Robbins TW. Planning and spatial working memory in Parkinson's disease. Journal of Neurology Neurosurgery and Psychiatry 1988; 51: 757 [39] Morris RG, Rushe T, Woodruff PWR, Murray RM. Problemsolving in schizophrenia-a specific deficit in planning ability. Schizophrenia Research 1995; 14 3 ; : 235 46. [40] Mortimer JA, Pirrozzolo FJ, Hansch EC, Webster DD. Relationship of motor symptoms to intellectual deficits in Parkinson's disease. Neuroloy 1982; 32: 133 [41] Noton D, Stark LW. Scanpaths in saccadic eye movements while viewing and recognizing patterns. Vision Research 1971; 11: 929 [42] Owen AM. Unpublished Ph. D. thesis. University of London 1982. [43] Owen AM. Cognitive planning in humans: neuropsychological, neuroanatomical and neuropharcological perspectives. Progress in Neurobiology 1997; 53: 431 [44] Owen AM, Beksinska M, James M, Leigh PN, Summers BA, Marsden CD, Quinn NP, Sahakian BJ, Robbins TW. Visuospatial memory deficits at different stages of Parkinson's disease. Neuropsychologia 1993; 31 7 ; : 627 44. [45] Owen AM, Downes JD, Sahakian BJ, Polkey CE, Robbins TW. Planning and spatial working memory deficits following frontal lobe lesions in man. Neuropsychologia 1990; 28: 1021 [46] Owen AM, Doyon J, Petrides M, Evans AC. Planning and spatial working memory examined with positron emission tomography PET ; . European Journal of Neuroscience 1996; 8: 353 [47] Owen AM, James M, Leigh PN, Summers BA, Marsden CD, Quinn NP, Lange KW, Robbins TW. Fronto striatal cognitive deficits at different stages of Parkinson's disease. Brain 1992; 115 6 ; : 1727 51. [48] Owen AM, Roberts AC, Hodges JR, Summers BA, Polkey CE, Robbins TW. Contrasting mechanisms of impaired attentional set-shifting in patients with frontal-lobe damage or Parkinson's disease. Brain 1993; 116 5 ; : 1159 75. [49] Owen AM, Sahakian BJ, Hodges JR, Summers BA, Polkey CE, Robbins TW. Dopamine-dependent fronto striatal planning deficits in early Parkinson's disease. Neuropsychology 1995; 9: 126 [50] Phillips ML, David AS. Visual scan paths are abnormal in deluded schizophrenics. Neuropsychologia 1997; 15 1 ; : 99 105 and leflunomide, for instance, aralen.

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