To date, a few cases of overdosage have been reported; the maximum dose taken was 3.6 g. All patients recovered without sequelae. There is no specific treatment in the event of overdose. In this case, symptomatic and supportive measures should be adopted. 5. 5.1 PHARMACOLOGICAL PROPERTIES Pharmacodynamic properties.
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Ii ; Being freely programmed in accordance with the requirements of the user; iii ; Performing arithmetical computations specified by the user; and iv ; Executing, without human intervention, a processing program which requires them to modify their execution, by logical decision during the processing run. B ; Automatic data processing machines may be in the form of systems consisting of a variable number of separate units. C ; Subject to paragraphs D ; and E ; below, a unit is to be regarded as being part of an automatic data processing system if it meets all of the following conditions : i ; It kind solely or principally used in an automatic data processing system; ii ; It is connectable to the central processing unit either directly or through one or more other units; and iii ; It is able to accept or deliver data in a form codes or signals ; which can be used by the system. Separately presented units of an automatic data processing machine are to be classified in heading 84.71. However, keyboards, X-Y co-ordinate input devices and disk storage units which satisfy the conditions of paragraphs C ; ii ; and C ; iii ; above, are in all cases to be classified as units of heading 84.71. D ; Heading 84.71 does not cover the following when presented separately, even if they meet all of the conditions set forth in Note 5 C ; above : i ; Printers, copying machines, facsimile machines, whether or not combined; ii ; Apparatus for the transmission or reception of voice, images or other data, including apparatus for communication in a wired or wireless network such as a local or wide area network iii ; Loudspeakers and microphones; iv ; Television cameras, digital cameras and video camera recorders; v ; Monitors and projectors, not incorporating television reception apparatus.
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The Members' Page gives you rapid access to all of the major tasks that you can perform within Derwent Drug File. The following information and links are found within the Members' Page.
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Pulmonary Laryngeal Cases - Sputum Smear AND Culture Negative: Source Case Investigations for children 5 with active TB disease: Extra-pulmonary cases: 1. Initial encounter 30 days after notification household contacts only ; 2. Medical history, exposure history and a physical assessment 3. Initial TST, if negative then no further action is needed 4. Initial TST, if positive then follow-up with a chest X-Ray 5. Place on LTBI treatment if indicated The contact investigation form #3126 ; should be accurately completed and signed on all index cases. Use the following codes as indicated: CODES.
Dilutions. And the numbers should be 10 in the first two, five in the second two, two in the third two. Patients like Wendy are 35 in the first two, 28 in the second two, 15 in the third two and anything above 15 will definitely kill an embryo. Since these cells secrete tumor necrosis factor alpha, one of the treatments that we utilize are the new Rheumatoid Arthritis medications called Remicade, Humira as well as Enbrel and the US government has been so convinced by my data that they patented me to utilize these medications, not for Rheumatoid Arthritis but for conditions of recurrent pregnancy loss and also implantation failure. And my hope is that we can now eventually get the FDA approval for these drugs to be utilized for this purpose because they truly work. Many of the patients that I see come to me with a history of endometriosis. They have been treated by their doctors, they have had the endometriosis cleared out, they have been able to take medications for them and the doctors have pronounced them cured but they go to try again and they have an exceedingly high incidence of implantation failure and recurrent pregnancy loss. We have found that if we treat the natural killer cells and, Jane, you help me? The success rate is 80%? Jane Reed: Dr Alan Beer: Jane Reed: I don't have it in front of but I think it was in the vacinity of 78 percent success rate versus. 39%? Yes, somewhere in the 78 percent pregnancy success rate versus something in the vacinity of 40 percent success rate when the drugs were not used. So there is a huge difference. Definitely ladies with endometriosis have a problem that continues even after the endometriosis has been removed and this problem is apparently immune because when you give them the immune treatments the pregnancies succeed. Can you speak a little bit louder please? I'm sorry. Wendy had put Jane on another telephone. Yes, I sorry. Basically I just said that ladies with endometriosis when they are using the immune therapies can have pregnancies with success rates of up to percent versus when they do not use immune therapies, I believe it is somewhere in the 40 or 50 percent ongoing pregnancy success rate. So the immune treatments are obviously making a difference. And this is even in ladies who have had their endometriosis removed. It's often been said that when the endometriosis is removed that they will be cured. However, they continue to fail unless they have the immune treatments. And this is something which is new and this is something that is not known and it's almost tragic in a way that some of these ladies are told that they are cured, so called, when they have had these expensive surgeries and then continue to fail. You know, and it's devastating, yet there are treatments. And that's what Dr. Beer is pioneering. The thing I hate the most about this disorder or this new disease is what it does to a woman's spirit. You lose trust in your body, you get pregnant and you will wait everyday what's going to happen today to loose my pregnancy again. And it's a kind of a rust of your hope machine and your spirit and there is really nothing that can cure that other than proving that your body is indeed made to have babies and you are able to prove it to yourself. So my hope for all of you out there and all you here is that if you are infertile and don't know the reason, if you have been through a failed pregnancy or failed cycle don't listen to the advice we will will get interested when you fail three. When a baby dies when a pregnancy fails something is wrong. And and letrozole.
Immunological mechanisms leading to graft rejection and sites of action of immunosuppressive drugs. Immunological mechanisms are shown in blue; immunosuppressive drugs and their site of action are shown in red. Acute rejection begins with recognition of donor antigens that differ from those of recipient by recipient antigen presenting cells APCs ; indirect allorecognition ; . Donor APCs carried passively in graft ; may also be recognized by recipient T cells direct allorecognition ; . Alloantigens carried by APCs are recognized by TCR-CD3 complex on surface of T cell. When accompanied by costimulatory signals between APC and T cell such as B7-CD28, T-cell activation occurs, resulting in activation of calcineurin. Calcineurin dephosphorylates transcription factor NF-AT, allowing it to enter nucleus and bind to promoters of IL-2 and other cytokines. IL-2 activates cell surface receptors IL-2R ; , stimulating clonal expansion of T cells T helper cells ; . IL-2, along with other cytokines produced by T helper cells, stimulates expansion of other cells of immune system. Activation of IL-2R stimulates TOR, which regulates translation of mRNAs to proteins that regulate cell cycle. Sites of action of individual drugs highlighted in red ; demonstrate multiple sites of action of these drugs, underscoring rationale for combination therapy. GC indicates glucocorticoid recepotor; BAS, basiliximab; and DAC, daclizumab.
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Owens J. 2006 drug approvals: finding the niche. Nature Reviews Drug Discovery. 2007; 6 2 ; : 99-101. Available at : nature nrd journal V6 n2 foll nrd2247 #f1. Accessed February 7, 2007.
CAPSULE SUSP RECON CAPSULE SUSP RECON TAB.SR 12H CAPSULE SUSP RECON TABLET VIAL FROZ.PIGGY PIGGYBACK PIGGYBACK VIAL FROZ.PIGGY VIAL TABLET SUSP RECON TABLET BUL BAG IN SUSP RECON FROZ.PIGGY VIAL PIGGYBACK TABLET PIGGYBACK TABLET VIAL CAPSULE SUSP RECON TABLET VIAL PORT FROZ.PIGGY ST Step Therapy 11 and lopid.
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Funding Support This project was funded by the National Institute for Health and Clinical Excellence who commissioned the National Collaborating Centre for Primary Care part of the Royal College of General Practitioners ; to produce guidelines for `The Diagnosis and Management of Chronic Fatigue Syndrome Myalgic Encephalomyelitis or Encephalopathy ; in Adults and Children'. The work forms part of the independent synthesis of research evidence to support the development of these guidelines. The views expressed in this publication are those of the authors and not necessarily those of the NCC-PC, RCGP or the Institute. The funding source had no influence on study design; in the collection, analysis, and interpretation of the data; in the writing of the report; and the decision to submit the paper for publication. Competing interests REFERENCES and lopressor.
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Allergies anti-depressants anti-infectives anti-psychotics anti-smoking antibiotics asthma cancer cardio & blood cholesterol diabetes epilepsy gastrointestinal hair loss herpes hiv hormonal men's health muscle relaxers other pain relief parkinson's rheumatic skin care weight loss women's health allegra atarax benadryl clarinex claritin clemastine periactin phenergan pheniramine zyrtec anafranil celexa cymbalta desyrel effexor elavil, endep luvox moclobemide pamelor paxil prozac reboxetine remeron sinequan tofranil wellbutrin zoloft albenza amantadine aralen flagyl grisactin isoniazid myambutol pyrazinamide sporanox tinidazole vermox abilify clozaril compazine flupenthixol geodon haldol lamictal lithobid loxitane mellaril risperdal seroquel nicotine zyban achromycin augmentin bactrim biaxin ceclor cefepime ceftin chloromycetin cipro, ciloxan cleocin duricef floxin, ocuflox gatifloxacin ilosone keftab levaquin minomycin noroxin omnicef omnipen-n oxytetracycline rifater rulide suprax tegopen trimox vantin vibramycin zithromax advair aerolate, theo-24 brethine, bricanyl ketotifen metaproterenol proventil, ventolin serevent singulair arimidex casodex decadron eulexin femara levothroid, synthroid nolvadex provera, cycrin ultram vepesid zofran acenocoumarol aceon adalat, procardia altace atenolol amlodipine avapro caduet calan, isoptin capoten captopril hctz cardizem cardura catapres cilexetil, atacand clonidine, hctz combipres cordarone coreg coumadin cozaar dibenzyline diovan fosinopril hydrochlorothiazide hytrin hyzaar inderal ismo, imdur isordil, sorbitrate lanoxin lasix lercanidipine lopressor lotensin lozol micardis minipress moduretic normadate norpace norvasc plavix plendil prinivil, zestril prinzide rythmol tenoretic tenormin trental valsartan hctz vaseretic vasodilan vasotec zebeta crestor lipitor lopid mevacor pravachol tricor zocor accupril actos alpha-lipoic acid amaryl avandia diamicron mr gliclazide metformin glucophage glucotrol glucotrol xl glucovance lyrica micronase orinase prandin precose starlix depakote dilantin lamictal neurontin sodium valproate tegretol topamax trileptal valparin aciphex asacol bentyl cinnarizine colospa compazine cromolyn sodium cytotec imodium motilium nexium nexium fast pepcid ac pepcid complete prevacid prilosec propulsid protonix reglan stugil zantac zelnorm zofran propecia, proscar famvir rebetol valtrex zovirax combivir duovir-n epivir pyrazinamide retrovir sustiva videx viramune zerit ziagen aldactone calciferol danocrine decadron prednisone provera, cycrin synthroid avodart flomax hytrin levitra propecia, proscar viagra lioresal soma tizanidine ibuprofen zanaflex accupril alpha-lipoic acid amantadine aralen arcalion aricept ascorbic acid benadryl bentyl betahistine calciferol carbimazole compazine cyklokapron ddavp, stimate detrol dihydroergotoxine ditropan dramamine exelon florinef imitrex imuran isoniazid lasix melatonin myambutol nimotop orap persantine piracetam pletal quinine rifampin rifater rocaltrol strattera ticlid tiotropium urecholine urispas urso vermox zyloprim acetylsalicylic acid advil, medipren celebrex flunarizine imitrex ketorolac maxalt ponstel tylenol ultram benadryl ditropan eldepryl requip sinemet trivastal advil, medipren arava colchicine decadron feldene indocin sr mobic naprelan naprosyn zyloprim betamethasone differin nizoral oxsoralen prograf retin-a xenical advil, medipren allyloestrenol clomid, serophene diflucan evista folic acid fosamax isoflavone nexium parlodel ponstel prevacid prilosec progesterone provera, cycrin rocaltrol tibolone generic coreg generic name: carvedilol ; qty.
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Elevated troponin level. New or presumably new ST-segment depression at presentation. Recurrent angina ischemia with symptoms of heart failure, an S3 gallop, pulmonary edema, worsening rales, or new or worsening mitral regurgitation. High-risk findings on noninvasive ischemic testing; Left ventricular systolic dysfunction ejection fraction 40% on a noninvasive study ; . Hemodynamic instability or angina at rest accompanied by hypotension. Sustained ventricular tachycardia. Percutaneous coronary intervention PCI ; within six months. Prior coronary artery bypass grafting CABG ; . For a pocket version of the ACC AHA guidelines, see : acc clinical guidelines unstable unstable pkt. pdf. A PDA download is available.
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Objective: To investigate development of radiographic damage in hands and feet of patients with early rheumatoid arthritis RA ; monitored prospectively for 10 years, and to search for prognostic factors. Patients and methods: 181 patients with early RA mean disease duration one year ; were assessed annually with radiographs of hands and feet during years 05 and at year 10. Radiographs were evaluated according to Larsen range 0200 ; . Predictive factors for progressive disease for years 05 and 510 were evaluated by logistic regression analyses. Results: 82 168 49% ; patients had erosions at inclusion and almost all became erosive with time 90% after two years and 96% after 10 years ; . Radiographic progression was most rapid during the first two years and 75% of all damage occurred during the first five years. The median Larsen score increased from 6 at inclusion to 41 after five years and 54 after 10 years. Only 5.3% of all evaluated joints became maximally eroded, the second metacarpophalangeal joint being the most commonly affected. Mean ESR during the first three months and rheumatoid factor status were significant predictors for radiographic progressive disease, it was not possible to predict non-progressive disease. Conclusions: Joint damage in hands and feet developed early and progression was most rapid during the first years of disease. The different rates of progression at different stages should be considered in the design of trials of drugs aimed at retarding joint damage. Disease activity at study start influenced the degree of joint damage during the entire 10 years and
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4 ., .., , .. - . 2002. - XXXVIII. - C. 235-38 ; . 5 . : - 1975. - C. 175. 6. Occupational Health, The soldier and the industrial base. Uniformed Services University of the Health Sciences Bethesda. Maryland: 1993. - P. 207-216.
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Data for this evaluation were gathered from medical records of 207 patients admitted after 1st February 2001, excluding paediatric, maternity, boarders and day patients. Patient records were initially examined for documentation of antibiotic use, and where antibiotics were given the following details were recorded onto data sheets: age, gender and indigenous status; admission history clinical division, specialty, length of stay, acute or elective admission status, diagnosis, existing comorbidity and relevant adverse reactions antibiotic usage agents used, dose, route, frequency, duration and total number of doses as well as supporting diagnostic evidence such as radiology, microbiology and other pathology ; . Information was coded using computer spreadsheet software. Each course of antibiotics or episode was compared to recommendations of the Guidelines. The presenting diagnosis as described in the case records was assumed to be accurate, and the appropriateness of antibiotic use was judged on this basis. Demographic information was obtained from the Admission Registration Record, while clinical information was acquired from the Discharge Summary, Integrated Progress Notes and admission forms. Cases were categorised as either surgical or medical according to admission status. Some cases in this study were admitted under the care of a surgeon, but underwent no or only minor surgical procedures. Surgical cases were divided further into specialties on the basis of the procedure performed, but not necessarily the specialty of the surgeon. Each antibiotic episode was assessed in relation to the recommendations in the Guidelines, and categorised according to the following criteria, Significant Variance - when the preferred drug was not used or when the antibiotic used was not indicated; Minor Variance, - differences in dose, route or frequency of administration, Appropriate Use, -equates to observed practice being equivalent to the Guidelines. Variance was determined by objective comparison of documented prescribing with the recommendations of the Guidelines. Variations that were reasonably substantiated were usually considered appropriate, and doubts were generally resolved in favour of prescribers to avoid bias. This evaluation was conducted by Clin Prof J. A. Millar Chairman ; and Mr D. Lyon Research Officer ; on behalf of the WADTC, with the consent of the management and staff of Port Hedland Regional Hospital.
Western blotting analysis demonstrated the constitutive expression of TRPC1, C3, C4, TRPV1 and V4 in HUVECs. The increase in [Ca2 + ]i and non-selective cation currents were inhibited by the 3, 5-bis trifluoromethyl ; pyrazole derivative BTP2, 10nM ; which is known as a specific TRPCs channel blocker, but not by TRPVs blocker, ruthenium red. The quantitative PCR analysis showed that H2O2 treatment leads to increases of ICAM-1 mRNAs to the 1.8-fold levels of untreated cells. Moreover, the flow cytometry analysis showed H2O2 treatment increased the number of ICAM1-positive cells. Remarkably, all the above mentioned effects of H2O2 were attenuated by BTP2, but not by ruthenium red. [Conclusion] H2O2 increases ICAM-1 expression in HUVECs, partly through the activation of BTP2-sensitive TRPC channels. Keywords: transient receptor potential channel; hydrogen peroxide; ICAM-1 P-2. Therapeutic Potential of Ribbon type Oligodeoxynucleotide Decoy NF- B in Cardiovascular Diseases Mariana K. Osako, Naruya Tomita, Hironori Nakagami, Ryuichi Morishita Division of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan Objective: To test the ability of the Ribbon-type ODN RODN ; in block the NF- B transcriptional activity in TNFstimulated human vascular smooth muscle cells hVSMC ; . Methods: We evaluated the efficiency in the process of enzymatic ligation of R-ODN, the binding activity to NF- B, and the stability against Exonuclease III and nucleases present in serum. The functional activity of R-ODN to inhibit NF- B in vitro was evaluated in hVSMC: TNF induced proliferation rate and MMP-9 expression were assessed after R-ODN transfection. Results & Conclusion: Although RODN has a phosphodiester backbone, their physical conformation was designed to provide nuclease resistance without interfering with their binding activity. As expected, R-ODN showed more resistance to exonucleases and stability in 100% serum than non-modified ODN N-ODN ; . Importantly, and the construction did not interfere with its binding activity. Transfection of R-ODN significantly inhibited the expression of MMP-9 and the proliferation of VSMC induced by TNF- . Overall, the development of ribbon NF- B decoy ODN could provide a useful tool for basic and clinical research, for example, omeprazol.
The following resources will be available on-line, and can be accessed by clicking the "Symposium OnLine" link at sabcs : Abstracts On-Line, a searchable on-line database of SABCS abstracts, is made available through an educational grant from AstraZeneca Pharmaceuticals. The website also includes abstract databases from the 24th, 25th, and 26th Annual SABCS. Please note that this year's abstract books are also available, and can be ordered from the website. ; Posters2ViewTM will allow users to search, view, and download posters presented at SABCS. For those who missed presentations of interest, or who would like to review them, audio and video highlights of oral presentations will be available via streaming webcast. Slides and transcripts will also be included. This service is supported by an educational grant from AstraZeneca Pharmaceuticals and
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SECTOR: HEALTH - phase VI Subsector: 02-01 TITLE: Annex 01- National Master List of Drugs CODE DESCRIPTION 02-01-03138 02-01-03139 02-01-03140 Multilink LG. volume kit Concentrated phosphate buffer saline Liquid Dab substrate pack Counterstain 250ml ; Peroxide block Antigen retrieval AR-10 Antigen retrieval citra Trypsin Pepsin Protease Power block Optiplus postivie charged slides Paper pen Common AB diluent ANA screen micro plate ELISA x 96 test Anti DNA native antibadies x 96 test Anti cardio lipin IgM IgG x 96 test ENA profite x 96 test Anti RO soluble antigen x 96 test Anti LA soluble antigen x 96 test Anti SM soluble antigen x 96 test Anti SM- RNP soluble antigen x 96 test Anti scl -70 antigen x 96 test Anti JO- 1 Antigen x 96 test Anti centionese micro plate EIA x 96 test Anti Histone micro plate EIA x 96 test Anti Metochondria micro plate EIA x 96 test Anti thyroglobulin micro plate EIA x 96 test Anti thyroid peroxidase micro plate EIA x 96 test ENA micro plate EIA sample diluent conceitrated x 25ml AMA ENA micro plate EIA wash buffer conceitrated x 20ml DS DNA control set SM control set SM RNP control set La control set Scl -70 control set Jo -control set Anatutor Soft ware for micro plate reader I.F slide series.
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Details of the apparatus and methods employed have been fully described elsewhere.9 Briefly, the investigation was carried out in a quiet room with subdued lighting. The subject was seated in a stable chair that supported the back but not the head ; before a table on which was situated the lifting device. Subjects were positioned so that they were able to grip the object between their forefinger and thumb and lift and hold the object at the wrist while their elbow remained fully supported on a padded rest. The measuring instruments built into the device registered the grip force exerted on the object 9301b; Kistler, Winterhur, Switzerland ; and its vertical position T60500; VAC, Munchen, Germany ; . These signals were amplified and then passed to the analogueto-digital converter board NI-PCI-MIO-16XE; National Instruments, Austin, TX ; of a laboratory computer Macintosh PPC 7600 132; Apple, Cupertino, CA ; sampling each channel at 2.5 kHz. The subjects were required, without visual feedback concerning hand position, to grip and lift the object 4 to 6 above the table, then hold it steady for 6 to 8 seconds before replacing the object on the table and releasing it. The contact pads on the object for thumb and forefinger were covered with sandpaper extra-fine, corn 400 ; . A second laboratory computer Macintosh IIVX; Apple ; was used to control the load of the object via a servo-device. A torque motor attached via a nonelastic band to the object was used to alter object load between lifts without the subject's knowledge in a pseudo-random manner between two levels, namely 3.3 N light ; and 7.8 N heavy ; , such that five lifts could be selected for each load where the load remained unaltered from the preceding lift. A 10- to 15-second pause was allowed between each lift.
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On the other hand, manydrugs have been developed that exert an antiviral effect in patients through mechanisms that are not completely understood, for instance, paracetamol.
Because of the aging population, osteoporosis is now a major public health issue; however, the vast majority of women with osteoporosis still go undiagnosed, said jean-francois leprince, president, aventis pharma inc now more than ever, it is critically important that canadians recognize the urgency to diagnose and treat osteoporosis.
All three of these regimens use fda-approved drugs for the treatment of breast cancer.
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PRIMSOL Proloprim ; ZYVOX Beta-lactam, Cephalosporins Ceclor ; cefaclor Duricef ; cefadroxil hydrate Claforan ; cefotaxime sodium Vantin ; cefpodoxime proxetil Ceftin ; cefuroxime axetil cephalexin monohydrate Keflex ; Beta-lactam, Other LORABID Beta-lactam, Penicillins Augmentin ; amox tr potassium clavulanate Amoxil ; amoxicillin trihydrate Tegopen ; cloxacillin sodium Dynapen ; dicloxacillin sodium Oxacillin Sodium ; oxacillin sodium Piperacillin Sodium ; piperacillin sodium Macrolides BIAXIN XL ERYTHROCIN STEARATE Iloson4 ; erythromycin estolate E.E.S. 200 ; erythromycin ethylsuccinate KETEK KETEK PAK ZITHROMAX ZITHROMAX ZITHROMAX TRI-PAK ZMAX Quinolones AVELOX AVELOX ABC PACK FLOXIN LEVAQUIN LEVAQUIN Floxin ; ofloxacin Sulfonamides Sulfadiazine ; sulfadiazine sulfamethoxazole trimet Bactrim ; hoprim trimethoprim T-2.
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1-C. Macrolides azithromycin. * ZITHROMAX L ; clarithromycin. * BIAXIN L ; clindamycin. * CLEOCIN ERYTHROMYCIN BASE erythromycin EC. ERY-TAB erythromycin estolate. * ILOSONE erythromycin ethylsuccinate. * E.E.S. or * ERYPED erythromycin stearate. * ERYTHROCIN.
Nm, emission occurred from 350-650 nm with quantum yields ranging from 0.3- 0.03. Quantum yields for intrinsic fluorophores excited at their peak absorption wavelengths were 0.02 NADH, 340 nm ; , 0.035 FAD, 450 nm ; and 0.087 protoporphyrin IX, 408 nm ; . A review of the literature shows that these fluoroquinolones have a large volume of distribution and can be found in high concentrations in almost every organ during a treatment regime. The product of the drug tissue concentration and quantum yield, which we term the Fluorescence Effective Concentration, with certain assumptions, is such that it is likely these fluoroquinolones have the potential to interfere during fluorescence diagnosis techniques. 36 Photoinactivation of clinical multi-drug resistant pathogens in Hong Kong. Christine M Yow1, * , WM Lai2, * , KC Wong3, * , HM Tang1, * , Ellie S Chu1, * and Ricky W Wu1, * . 1Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, HKSAR, 2Department of Medical Microbiology, Prince of Wales Hospital, Shatin, Hong Kong, HKSAR, 3Department of Microbiology, United Christian Hospital, Kwun Tong, Hong Kong, HKSAR. Hypericin HY ; is one of the herbal therapeutic agents which has been extensively studied on tumor cells but nevertheless not on photobactericidal study. At present, methicillin-resistant Staphylococcus aureus MRSA ; , extendedspectrum beta-lactamase ESBL ; producing Escherichia coli and Klebsiella pneumoniae are three of the commonest multi-drug resistant MDR ; pathogens arouse worldwide concern. Here we explored the photodynamic inactivation PDI ; potential of HY on aureus MSSA ; , wild type Escherichia coli and wild type K. pneumoniae and compared with their clinical MDR isolates: MRSA, ESBL E. coli and ESBL K. pneumoniae. All bacterial strains were sensitised with a range concentrations of HY 0.5 - 80 M ; for hour and then exposed to light 10 - 30 Jcm-2 ; . Dark controls were included. After treatment, viable bacterial counts were enumerated for calculation of survival fraction. At 4 M and 30 Jcm-2 light dose, HY showed complete killing of MSSA and MRSA. At 80 M with 30 Jcm-2, only 80% killing of E.coli WT ; and ESBL E. coli; whereas 50% killing of K. pneumoniae WT ; and ESBL K. pneumoniae were obtained. This suggested that Hypericin were effective to MRSA and MSSA but not the gram negative ESBL pathogens in this study. Acknowledgement: This project was supported by Internal Competitive Research Grant ICRG PolyU A-PF33, 2004. 37 Reintroduction of a classic vitamin D UV source. R. M Sayre1, 2, * , J. C Dowdy2, * and J G Shepherd3, * . 1Dept. of Medicine, Division of Dermatology, Memphis, TN, USA, 2Rapid Precision Testing Laboratory, Cordova, TN, USA, 3KBD, Inc, Cresent Springs, KY, USA. Beginning around 1930 sunlamps claiming to provide ultraviolet UV ; exposure to make vitamin D were sold to the.
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