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40. Schultz GW. A study of Bancroftian filariasis on the islands of Bataan and Rapu, Philippines. Southeast Asian J Trop Med Public Health 1988; 19: 207-14. Ramaiah KD, Vijay Kumar KN, Ramu K. Knowledge and beliefs about transmission, prevention and control of lymphatic filariasis in rural areas of South India. Trop Med Int Health 1996; 1: 433-8. Rifkin S. Paradigms lost: toward a new understanding of community participation in health programmes. Acta Trop 1996; 61: 79-92. Babu BV, Satyanarayana K. Factors responsible for coverage and compliance in mass drug administration during the programme to eliminate lymphatic filariasis in the East Godavari District, South India. Trop Doct 2003; 33: 79-82, because val susa.
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O Ranked among the top 10 best companies in India in 2002, 2003 and 2004 by Forbes Global magazine. O Ranked 5th with a 3.35% market share and twice industry growth rate in the domestic Indian pharmaceutical market. O Ranked highest for products in fields of psychiatry and neurology in India, highest for cardiology, second in gastroenterology, fourth in ophthalmology and among chest physicians, fifth among all physicians, based on CMARC ranks. Top core areas for Sun Pharma account for over 70% of India dosage-form sales. O Revenues in 2003-04 reached $255 million up from $224 million and net profit rose to $79 million, up from $56.3 million. Income was up 14% and net profit up 45% over the previous year. * O Two new-drug research centers spread over 250, 000 square feet of research area, of which one primarily conducts work for Caraco. The other is a new research campus for drug discovery, spread over 16 acres, * $1 INR 44 inaugurated recently by the President of India. About 400 people are engaged in R&D activity. O The Company operates four active-drug manufacturing facilities, two of which are USFDA approved plants. The Company also has five formulationmanufacturing plants. One plant holds USFDA and UKMHRA approvals. O Introduced 44 new drugs for various indications during 2004-05, 21 of which were delivery system based, or technically challenging to develop. The Company currently has 102 active bulk drugs in its formulary, some of which are for products transferred to Caraco. O Highly focused management team strengths lie in specialty products, vertical integration, product development, highly cost efficient. O More than 4, 000 employees in India, of which more than 2, 000 are field medical representatives. O Holds approximately 63% of the common stock of Caraco.
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Is Cassytha filiformis L. holding some potential as a source of drugs for the treatment of Parkinson's disease? Cryptocarya griffithiana Wight is a tree that grows to a height of 20 m the lowland rainforests of Burma, Thailand, Malaysia, the Philippines, and Indonesia. The stems are stout and covered with a rusty tomentum. The leaves are simple, spiral, exstipulate, leathery, elliptic, and up to 32 long. The fruits are globose, glossy, and green Fig. 76 ; . The bark of this plant has the reputation among Malays and Indonesians of being poisonous. The pharmacological potential of this tree is unexplored. Note that Cryptocarya species are very interesting, as they have the tendency to elaborate a series of stilbenes derivatives known as -pyrones 112, 113 ; . The neuropharmacological potential of such.
Ated with contact lens wear. The classic presentation involves a patient in extended-wear hydrogel contact lenses who, upon awakening, experiences ocular pain e.g., foreign body sensation ; , tearing, variably decreased vision and photophobia. Clinically, CLARE manifests as an acute keratitis marked by mid-peripheral corneal infiltrates in the most severe cases.1 These infiltrates may emanate from and accumulate near encroaching limbal vessels. Associated clinical signs include moderate-to-severe conjunctival and limbal hyperemia, corneal edema and mild-to-moderate blepharospasm. Pronounced lid edema, corneal epitheliopathy and anterior chamber reaction are notably absent. Often, patients with CLARE will have a history of poor contact lens hygiene, excessive wearing time or frank contact lens abuse. In some cases, the contact lens shows inadequate movement, and the patient may be physically unable to remove the lens from the eye during the initial episode. Immobility of the lens is, however, not uniformly encountered. CLARE may occur both with wellfitted and poorly-fitted lenses and may be seen with low or high dK L materials, including silicone hydrogels and gas permeable lenses.2, 3.
Kingdom, standard practice 497 following a trial by the British Medical Research Council demonstrating faster conversion, fewer bacteriologic failures and relapses. 496, 498 The WHO considered it one of the major regimens for low-income countries. 499 It took many years for experts of other countries to be convinced of its importance, and that only after an international comparative clinical trial. 500, for example, susa.
Hydroxybutyrate GHB ; is an endogenous psychotropic compound thought to function as a neurotransmitter or neuromodulator in the mammalian brain. Although some of its effects may be mediated by GABAB receptors, the presence of high-affinity [3H]-GHB binding sites in the brain suggests the existence of a GBH receptor. In the October issue of J. Pharmacol. Exp. Ther., Wellendorph et al. report the development of novel, smallmolecule, high-affinity, conformationally restricted ligands for this putative GHB receptor that have little affinity IC50 1 mM ; for GABA receptors. The best of these new GHB analogs has an affinity nearly forty-times that of GHB for highaffinity GHB binding sites, and several analogs inhibit the binding of [3H]-NCS-382 a specific GHB binding site ligand ; to high-affinity sites. These new ligands are powerful tools to probe the function of GHB and to characterize the physiological significance of the putative GBH receptor. [Wellendorph.
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