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Apart from primary hypertension, ARBs are also recommended for first-line usage in reduction of blood pressure in diabetic nephropathy patients. Being the latest entry into the hypertension market, several of today's biggest brands belong to the ARB class, among them Novartis's Diovan, Merck's Cozaar and Sanofi's Avapro, as well as the recently launched Benicar DaiichiSankyo Forest ; and Boehringer's Micardis. However, although the ARB class commands no more than a 14% prescription market share, it did show an aboveaverage increase of 14% in 2004, mainly driven by expanding the existing franchise not only at the expense of older classes coming off patent, but also by fixed combination formulations with diuretics such as hydrochlorothiazide Hyzaar, Avalide, CoDiovan Diovan HCT ; , Atacand HCT ; . We expect the class to continue to grow until 2010 before Merck's Cozaar becomes the first main brand to succumb to generic competition followed by Novartis's Diovan in 2012 ; . Excluding Rasilez and other renin inhibitors, the only class expected to grow over the next few years are the ARBs. Even assuming aggressive generic erosion of Cozaar from 2010 onwards, the main brands in the class are expected to grow by 2% on average without Rasilez.
As described previously, the second data source in the external analysis of the Texas foster care population is a random sample n 472 ; extracted from the total July 2004 foster care population. The sample represents approximately 7.3% of the 6, 459 youth enrollees with one or more psychotropic medications during the study month. The sample excludes youth with mental retardation approximately 3% of the total ; and medically fragile approximately 6-7% of the total ; to avoid mixing very complex special cases with the general foster care population. The smaller sample allowed more sophisticated analysis related to polypharmacy, a major issue in the quality of psychotropic drug therapy. The age group in this analysis includes youths 0-19 years of age, because micardis at.
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71 ; KISSEI PHARMACEUTICAL CO., LTD. [JP JP]; 19-48, Yoshino, Matsumoto-shi, Nagano 399-8710 JP ; . for all designated States except pour tous les tats dsigns sauf US ; 72, 75 ; MOMOSE, Denichi [JP JP]; 1557-1, Oaza Satoyamabe, Matsumoto-shi, Nagano 390-0221 JP ; . IKEGAMI, Kazuhiko [JP JP]; 581-D, Oaza Shimadachi, Matsumoto-shi, Nagano 390-0852 JP ; . TAKEDA, Yasuhiro [JP JP]; Kissei Daisanseiyu-ryo, 4509, Oaza Kashiwabara, Hotaka-machi, Minamiazumi-gun, Nagano 399-8304 JP ; . 81 ; AE ZW. 84 ; AP GH A61K 35 00, C12N 15 63, G06K 9 00, F21K 2 00, A61B 10 00 11 ; 56582 21 ; PCT IL01 00092 22 ; 31 Jan jan 2001 31.01.2001 ; 25 ; en 30 ; 179, 139 ; 60 258, 038 ; en 31 Jan jan 2000 31.01.2000 ; 27 Dec dc 2000 27.12.2000 ; US US 13 and
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In her letter, Ziem raises the issue of exacerbations of respiratory illness and other health effects of pesticide exposure that we did not measure in our study Karpati et al. 2004 ; . Our analysis was designed to evaluate only whether a population-level effect on emergency department visits, specifically on asthma and other respiratory illnesses, was evident following pyrethroid pesticide spraying. Similar study designs, despite their limitations, have proven to be sensitive methods of identifying population-level health impacts from exposure to criteria air pollutants from exposure to unusual events, such as smoke from forest fires. Moreover, our analysis did identify adverse population-level health effects of elevated ozone and particulates. As we noted in our discussion, the results of the analysis for pesticide exposure do not rule out the possibility that certain individuals might have been affected by exposure to the agent. Also, our focus was on emergency department visits, which generally signify more serious illness, although in urban neighborhoods even milder illnesses are often treated in such settings. However, if, in fact, certain individuals experienced asthma exacerbations following exposure, we believe our study demonstrates that their number was small enough that it did not result in a population-level increase in emergency department visits for asthma and chronic obstructive pulmonary disease. In our analysis we evaluated only respiratory complications of pesticide spraying to control West Nile virus, and we did not purport to measure possible neurotoxic or other nonrespiratory effects. Also, we did not evaluate the efficacy of pesticide spraying for mosquito control or its costbenefit ratio with regard to pesticide-related health effects and
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The functional food and drinks market was worth $26.4bn in Europe and the US in 2005. It continues to grow at a CAGR of 4.4%, driven by consumers' increasing acceptance of functional foods and a desire to self-medicate. The food and drinks industry is adopting pharma technologies in order to create more sophisticated and personalized health products. These technologies include genomics, transcriptomics, metabolomics and nanotechnology. Labelling and health claim regulations are likely to change globally as a result of the evolution of functional food and drinks. These changes are likely to include issues such as harmonization of regulatory guidelines and more extensive clinical trials. A major growth area for Nestl is heart health. In 2004, of all the functional products launched by the company, only 6.5% were heart health products, but this share increased to 29.7% in 2006 and
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VPHP is very pleased to announce the commencement of a new network-wide quality initiative, with a patient based focus, that will educate and strengthen each practitioner's skill set when delivering quality care to culturally diverse populations. The American's Health Insurance Plans AHIP ; Association is one of VPHP's partners in Quality. AHIP is the national association representing nearly 1, 300 member companies providing health insurance coverage to more than 200 million Americans, including Medicaid recipients. Two of AHIP's goals, as well as VPHP's, include expanding access to high quality and cost effective health care to all Americans. AHIP has developed a Continuing Medical Education Course 1.0 Category, 1 Credit toward AMA's Physician Recognition Award ; that addresses Cultural Competency. Please find the specifics below: The course is FREE. The Course takes 20 minutes. Please access the website: s: lms.qualityinteractions AHIPSitelet Sitelet index ?CID 129&UID 4175 You will learn how to: Communicate effectively across cultures Identify issues related to health disparities Define common terms related to cross-cultural communication Review three business, medical, and legal reasons for improving cultural competency Assess key concepts on cross-cultural care VPHP strongly encourages each participating practitioner to complete this course, as it can improve the quality of care you deliver to VPHP patients and your other patients of diverse populations. Once you have completed the course and received your CME Certificate, please mail a copy of your CME Certificate to VPHP at the address below to be included in your credentialing file: Credentialing Department Supervisor Manager P.O. Box 5307 Richmond, VA 23220-0307 If you have questions regarding this new network-wide quality initiative, please feel free to contact Jamie W. McPherson, MPA, BSN, Director of Quality Improvement at 800-727-7536 ext. 5179 or email her at jmcpherson vapremier and
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Sewage system and on to a water treatment plant not designed to remove them. Unused drugs get flushed down the toilet or sink mothers have been told to do this for the safety of children ; . Hospitals and nursing homes dispose of vast quantities of pharmaceuticals, untouched when residents change or discontinue medications, or die. Drugs taken in life's home stretch likely contaminate posthumously, leaching from cemeteries into groundwater. Farmers give veterinary drugs to their animals, including large amounts of antibiotics. Drug-contaminated sewage sludge is sold as farm fertilizer. The resulting "chemical soup" with concentrations as little as one part per trillion causes chronic exposure to multiple bioactive substances that may well harm human health, even at low levels. Drugs are designed to have effects in small quantities; they are not meant to be mixed, willy-nilly. Researchers are discovering "windows of vulnerability, " when developing embryos are exquisitely sensitive to even minute amounts of chemicals. Since environmental tests for these and
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Polydimethylsiloxanes have low surface tension, with a critical surface tension around 24 mN m and a liquid surface tension around 20.4 mN m at 20C. As a result, PDMS polymers not only spread easily and form thin films over substrates such as skin and other organic substrates, but they are also able to spread over their own absorbed film. This allows silicones to wet, spread and subsequently adhere to skin. Coupled with visco-elastic behavior, this property reinforces the silicone ability for adhering to skin and subsequently releasing from skin, thus performing as expected as true pressure sensitive adhesives. Compared to other hydrophobic polymers, PDMS is very permeable to the diffusion of various substances including gases, water vapor and active drugs. These are appropriate properties for transdermal and topical drug delivery applications. Finally, some methyl groups can be substituted by other organic groups or atoms e.g. hydrogen, hydroxyl, vinyl, polyethylene oxide, methoxy, fluoride group ; , when specific chemical and physical properties are desired, such as adhesion to a certain substrate, higher or lower polarity, better thermostability, enhanced hydrophilicity, compatibility with other organic materials or targeted reactivity. This capability to functionalize the polydimethylsiloxanes is critical for transforming liquid or highly flowable materials into thermoplastic or thermoset materials that are represented respectively by visco-elastic silicone pressure sensitive adhesives PSA ; and by elastomeric silicone soft skin adhesives SSA ; . The broad spectrum of physico-chemical properties of the siloxane chemistry translates to multi-functional performances, flexibility in choice of silicone solutions and versatility in formulations, as shown in Figure 2. This is particularly useful to an adhesive formulator in designing the silicone adhesive composition to meet unique application needs.
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Center, Kolkata conducted this CME on Epilepsy. The participants included general practitioners and neurologists from all over the town. Dr. B K Swain delivered the introductory talk and introduced the speakers. Dr. Amlan Mandal spoke on `Febrile Seizure and Febrile SeizurePlus Syndrome'. In his lecture, he emphasized that febrile seizure is a benign syndrome with excellent prognosis. Dr. Debasish Choudhury, in his lecture `Management of Status Epilepticus' discussed the pre-hospital and hospital management of Status Epilepticus. Dr. Rajesh B. Iyer presented on the topic `Difficult to treat Epilepsy: Approach and Management'. He stressed on the early recognition of medical refractory cases and their proper management. Dr. Sujoy Sanyal, the last speaker of the session, spoke on `Surgically Remediable Epilepsy' focusing on those patients on whom treatment using medical therapy has failed. The entire session was very lively with a lot of interaction among the delegates and the speakers. A total of 45 delegates attended the Clinic. The Third Free Epilepsy Camp was conducted by the Department of Neurology on 11th December, 2005. A total of 32 patients received consultation from our Neurologist and Epileptologist. The Epilepsy Camp shall be held on the third Saturday of every month, for example, what is micardie hct.
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