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The Court may review the Special Master's Findings de novo. State ex rel Oregon State Bar v. Lenske, 284 Or 23, 26, 584 P2d 759 1978 ; . However, when the Special Master's Findings are unchallenged, the Court should accept those findings as the recommendation of the Court officer who has most carefully examined the facts during a six-month process. Petitioner, like respondents, has the responsibility of identifying those facts with which she disagrees and the reasons for her disagreement. See Naito v. Naito, 125 Or App 231, 864 P2d 1346 1993 ; failure to timely object to special master's findings and report waives party's ability to do so afterward ; . Consequently, except for the few disagreements noted by the parties, the Court should adopt the Special Master's Findings in full, as well as those supplemental facts from the record identified by respondents that are consistent with the Special Master's Findings. C. Argument. The Contract Clause states, "No * * * law impairing the obligation of contracts shall ever be passed * * * ." Or Const, Art I, 21. To establish a violation of the Contract Clause or prevail on a breach of contract claim, petitioner must first establish the existence of a contractual right. Hughes v. State of Oregon, 314 Or 1, 13-14, 838 P2d 1018 1992 ; Contract Clause Pendleton Grain Growers v. Pedro, 271 Or 24, 28, 530 P2d 85 1975 ; breach of contract ; .3 Oregon courts impose the same requirements for proving a statutory An impairment of a contract is distinguishable from a breach of contract in that an impairment removes the legal obligation of the contract such that there is no remedy for the violation. Eckles v. State of Oregon, 306 Or 380, 400, 760 P2d 846 1988 ; . In other words, it is the "distinction between a failure or refusal to perform according to the terms of a contract and an assertion of the invalidity or nonexistence of the contract terms under which that performance is specified. A failure or refusal to perform a contract is not inconsistent with recognition of the contract's validity." Id. Prohosting buy link lotensin cheapest lotensin buy link myblog lotensin lotensin 9 00 lotensin online pharmacy lotensin for sale lotensin cod cheap lotensin free shipping lotensin no prescription xenical hgh lotensin quit smoking detox discount lotensin lotensin on line lotensin hcl lotensin sale advanced book guest lotensin buy cheap eteamz and zocor.

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SHINGO KAWAMURA, YIPING LI, MITSURU SHIRASAWA, 1 NOBUYUKI YASUI and HITOSHI FUKASAWA1 Departments of Surgical Neurology and 1Pathology, Research Institute for Brain and Blood Vessels-AKITA, Akita 010-0874 The protective effects of a Ca2 + antagonist, nilvadipine, on focal cerebral ischemia were studied in male spontaneously hypertensive rats. The animals received either nilvadipine 3mgkg -1day-1 ; or a vehicle subcutaneously. Group 1 n 11 ; was treated for 7 days, and Group 2 n 11 ; for 14 days. The middle cerebral artery was occluded on the 6th Group 1 ; or 13th Group 2 ; day of the treatment, and neuropathological outcomes were quantified 24 hours later. The mean arterial blood pressure was significantly reduced with nilvadipine to normal levels. The % infarct volumes of Groups 1 372 ; and 2 343 ; were significantly less than those of their controls 393 [n 11] and 404 [n 12], respectively ; , although the difference between Groups 1 and 2 was not significant. When infarct areas were compared in each of 8 coronal sections, the infarct size had decreased in the 5 posterior sections in Group 2, but only in 2 sections of Group 1. A significant decrease in the edema volumes was observed in Group 2, but not in Group 1. Thus, nilvadipine provided protective effects against cerebral ischemia in rats having chronic hypertension, and the effects were dependent on the duration of treatment. Key words antihypertensive therapy; Ca2 + entry blocker; focal cerebral ischemia; spontaneously hypertensive rats 1998 Tohoku University Medical Press. In the CCOP Research Base's application for grant renewal, we proposed shifting our trial portfolio toward the evolving and unique strength of M. D. Anderson faculty members in the areas related to cancer control. Specifically, we have partnered with five key program leaders in Integrative and Behavioral Medicine Dr. Lorenzo Cohen ; , Symptom Management and Palliative Care Dr. Eduardo Bruera ; , Supportive Oncology Dr. Saroj Vadhan-Raj ; , Cancer Survivorship Dr. Robert Gagel ; , and Symptom Science Dr. Charles Cleeland ; . This series of articles will introduce these leaders and the valuable experiences they bring to CCOP. Dr. Lorenzo Cohen joined The University of Texas M. D. Anderson Cancer Center in 1997 and currently serves as an associate professor in the Department of Behavioral Science and as director of the Integrative Medicine Program. Dr. Cohen conducts research, which examines intervention programs that can reduce the sequelae of a cancer diagnosis and treatment and improve quality of life. Currently open to CCOPs and Main Members is Dr. Cohen's phase III trial studying mindfulness relaxation for reduction of chemo-induced nausea. 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Provided QoL data. Scores were awarded for each of the individual QoL parameters and, in this case, the data were analysed overall and in terms of baseline Pt-sensitivity i.e. Pt-r and Pt-s patients ; . However, the scores for the single QoL questions dyspnoea, sleep disturbance, appetite loss, constipation, diarrhoea and financial impact ; were not presented. At 12 weeks of follow-up, 23.4% 55 235 ; of topotecan patients and 28.5% 68 239 ; of caelyx patients had improved or stable global QoL scores, and 20.4% 48 235 ; of topotecan- and 20.5% 49 239 ; of caelyx-treated patients had worsened global QoL scores based on ITT data ; . Neither of these observations were statistically significant RR 0.823, 95% CI, 0.605 to 1.122 and RR 0.966, 95% CI, 0.700 to 1.418, respectively ; . The numbers of patients with maintained or improved scores for each of the subscales dependent on their Pt-sensitivity at baseline is shown in Figures 1214, along with the calculated corresponding RRs. Despite the minimal differences overall in patient QoL between topotecan and caelyx , the number of patients all patients ; with a maintained or improved pain subscale at 12 weeks showed a statistically significant difference in favour of topotecan RR 1.264, 95% CI, 1.076 to 1.500; see Figure 12 ; . This significant difference favouring topotecan was maintained in the Pt-s subgroup RR 1.54, 95% CI, 1.211.

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